Magnus MR (Morphine Sulphate) 30mg 10 Tablets / Strip

Generic:Morphine Sulphate MAGNUS MR 30 MG CAPSULES

Therapeutic Class:Narcotic analgesic

Composition:Magnus MR 10 mg capsule, containing morphine sulphate 10 mg Magnus MR 30 mg capsule, containing morphine sulphate 30 mg

Description:Morphine applies an agonist effect at saturable opioid receptors in the CNS and other tissues & acts as opioid analgesic. Morphine, an analgesic drug, treats acute and chronic pain. Pain of various origins (e.g., arthritis, fibromyalgia, cancer) is often linked to obesity, leading to an increased demand for analgesic drugs. Drug pharmacokinetics undergo alterations due to obesity, and certain drugs have proposed specific prescription methods for obese patients. However, scant data are available regarding the pharmacokinetics and pharmacodynamics of morphine in obesity.

Prescription of morphine depends on pain relief but the occurrence of respiratory adverse effects correlates with obesity. It is not currently taken into account. Variations in the volume of distribution, elimination half-life and oral clearance of morphine. In recent advances in the respective roles of drug-metabolizing enzymes, catechol-O-methyltransferase. The μ opioid receptor in morphine pharmacokinetics and pharmacodynamics, may contribute to differences between obese and non-obese patients. In addition, drug-drug interactions may alter the disposition of morphine and its glucuronide metabolites and which may either increase the risk of adverse effects or reduce drug efficacy.

Indications:Severe chronic pain or pain resistant to other analgesics, in particular pain associated with cancer.

Dosage:Adults:Recommended dosage is one capsule twice daily and at 12-hour intervals.Elderly: As with all narcotics a reduction in dosage may be advisable in the elderly, as appropriate.

Presentations:10 mg tab 30’s30 mg tab 30’s